Table 5 Characteristics of the propensity-matched cohort.

From: De-escalation of radiation therapy in patients with stage I, node-negative, HER2-positive breast cancer

 

Received RT (N = 504)

RT omission (N = 504)

Standardized difference

Age

Mean (SD)

63.7 (11.0)

64.0 (11.6)

0.0340

≥70 yrs, N (%)

207 (41.1%)

204 (40.5%)

0.0121

Comorbidities

  

0.0097

0

398 (79.0%)

396 (78.6%)

 

≥1

106 (21.0%)

108 (21.4%)

 

Laterality

  

0.0596

Left

261 (51.8%)

246 (48.8%)

 

Right

243 (48.2%)

258 (51.2%)

 

Hormone status

  

0.0276

ER+ or PR+

382 (75.8%)

376 (74.6%)

 

ER−/PR−

122 (24.2%)

128 (25.4%)

 

Treatment group

  

0.0309

HS and received ET

188 (37.3%)

182 (36.1%)

 

HS, no ET

194 (38.5%)

194 (38.5%)

 

ER−/PR−

122 (24.2%)

128 (25.4%)

 

Tumor size

  

0.0594

≤1 cm

156 (31.0%)

170 (33.7%)

 

>1–2 cm

348 (69.0%)

334 (66.3%)

 

Tumor grade

  

0.0122

Grade 3

260 (51.6%)

257 (51.0%)

 

Grade 1–2

221 (43.9%)

224 (44.5%)

 

Unknown

23 (4.5%)

23 (4.5%)

 

Facility type

  

0.0281

Academic

147 (29.2%)

150 (29.8%)

 

Other

344 (68.3%)

343 (68.1%)

 

Unknown

13 (2.5%)

11 (2.1%)

 

Race/ethnicity

  

0.0734

NH-White

407 (80.7%)

393 (78.0%)

 

NH-Black

43 (8.5%)

50 (9.9%)

 

Hispanic

25 (5.0%)

30 (6.0%)

 

NH-Other

25 (5.0%)

26 (5.1%)

 

Unknown

4 (0.8%)

5 (1.0%)

 

Income status

  

0.0082

<$46,000/yr

282 (56.0%)

284 (56.4%)

 

≥$46,000/yr

204 (40.5%)

202 (40.1%)

 

Unknown

18 (3.5%)

18 (3.5%)

 

No HSD

  

0.0084

≥20%

178 (35.3%)

180 (35.7%)

 

<20%

308 (61.1%)

306 (60.7%)

 

Unknown

18 (3.6%)

18 (3.6%)

 

Distance to facility

   

≥8.9 miles

242 (48.0%)

251 (49.8%)

0.0357

<8.9 miles

262 (52.0%)

253 (50.2%)

 

Chemotherapy

  

0.0787

Single-agent

213 (42.2%)

198 (39.3%)

 

Multi-agent

283 (56.2%)

294 (58.3%)

 

Not specified

8 (1.6%)

12 (2.4%)

 
  1. RT radiation therapy, SD standard deviation, HS hormone-sensitive (ER+ and/or PR+), ET endocrine therapy, NHW non-Hispanic white, NHB non-Hispanic Black, HSD high-school diploma.