Table 1 Frequency and distribution of AQP1 expression in association with established sociodemographic and oncological features of TNBC patients.

From: RIPK1 is a negative mediator in Aquaporin 1-driven triple-negative breast carcinoma progression and metastasis

 

Overall (n = 62)a

AQP1 expression

RIPK1 expression

Low (n = 31)

High (n = 31)

p Valueb

Low (n = 31)

High (n = 31)

p Valueb

Age

   

0.437

  

0.796

≤50 years

37 (59.7)

20

17

 

18

19

 

>50 years

25 (40.3)

11

14

 

13

12

 

BMI

   

0.167

  

0.490

≤24 kg/m2

52 (83.9)

28

24

 

25

27

 

>24 kg/m2

10 (16.1)

3

7

 

6

4

 

Tumor size

   

0.118

  

0.479

≤2 cm

11 (17.7)

4

7

 

7

4

 

2–5 cm

26 (41.9)

17

9

11

15

 

>5 cm

25 (40.4)

10

15

 

13

12

 

Lymph node status

   

0.005

  

0.022

Negative

29 (46.8)

20

9

 

10

19

 

Positive

33 (53.2)

11

22

21

12

 

Histological grade

   

0.445

  

0.203

1

0 (0)

0

0

 

0

0

 

2

29 (46.8)

16

13

12

17

 

3

33 (53.2)

15

18

 

19

14

 

Surgery

   

0.374

  

0.038

Breast conserving

15 (24.2)

9

6

 

4

11

 

Ablative

47 (75.8)

22

25

27

20

 

Radiotherapy

   

0.002

  

0.013

No

19 (30.6)

15

4

 

5

14

 

Yes

43 (69.4)

16

27

26

17

 
  1. aThe data are displayed as No. (%).
  2. bχ2 test.
  3. Abbreviations: TNBC, triple-negative breast cancer; BMI, body mass index.
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