Table 2 Multivariate Cox regression model stratified by treatment for the variables used by composite risk score assessment.
Log (HR) | HR | 95% CI | P value | |
|---|---|---|---|---|
Age | ||||
<35 | 0.425 | 1.53 | 0.72–3.24 | 0.268 |
35–39 | 0.859 | 2.36 | 1.39–3.99 | 0.001 |
40–44 | 0.113 | 1.12 | 0.68–1.84 | 0.665 |
45–49 | 0.000 | 1.00 | Ref. | |
≥50 | 0.322 | 1.38 | 0.94–2.03 | 0.100 |
Nodes | ||||
1–3 | 0.000 | 1.00 | Ref. | |
≥4 | 0.737 | 2.09 | 1.61–2.71 | <0.001 |
Tumor size | ||||
≤2 | 0.000 | 1.00 | Ref. | |
>2 | 0.577 | 1.78 | 1.36–2.34 | <0.001 |
ER (%) | ||||
<50 | 0.262 | 1.30 | 0.92–1.82 | 0.135 |
≥50 | 0.000 | 1.00 | Ref. | |
PGR (%) | ||||
<20 | 0.293 | 1.34 | 0.96–1.86 | 0.083 |
20–49 | 0.140 | 1.15 | 0.82–1.62 | 0.418 |
≥50 | 0.000 | 1.00 | Ref. | |
Histological grade | ||||
G1 | 0.000 | 1.00 | Ref. | |
G2 | 1.022 | 2.78 | 1.13–6.80 | 0.026 |
G3 | 1.092 | 2.98 | 1.20–7.40 | 0.018 |
Ki-67 (%) | ||||
<14 | 0.000 | 1.00 | Ref. | |
14–19 | 0.166 | 1.18 | 0.75–1.85 | 0.483 |
20–25 | 0.068 | 1.07 | 0.72–1.58 | 0.741 |
≥26 | 0.095 | 1.10 | 0.77–1.57 | 0.605 |
