Fig. 7: Correlation between the expression of MIR200CHG and miR-200c/141-3p. | npj Breast Cancer

Fig. 7: Correlation between the expression of MIR200CHG and miR-200c/141-3p.

From: Long non-coding RNA MIR200CHG promotes breast cancer proliferation, invasion, and drug resistance by interacting with and stabilizing YB-1

Fig. 7

a, b Analysis of the expression of miR-200c/141-3p in the TCGA breast cancer array. ***P < 0.001. Boxplots represent medians (center line) and interquartile range (IQR; box), and whiskers represent the maximum and minimum values within 1.5 times the IQR from the edge of the box. c, d Correlations between the expression of MIR200CHG and miR-200c/141-3p were analyzed by TCGA breast cancer array. e Expression of miR-200c/141-3p in breast cancer cell lines (MCF7, T-47D, BT-549, MDA-MB-231) was analyzed by qRT-PCR. Data were confirmed in three independent experiments and are represented as mean ± SEM in triplicates. f The effect of MIR200CHG knockdown or overexpression on the expression of miR-200c/141-3p in breast cancer cells was analyzed by qRT-PCR. The experiment was carried out in triplicate and repeated at least three times. Data are represented as mean ± SEM, and analyzed by two-tailed T test. *P < 0.05.

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