Table 3 Mean risk scores for each threshold.

From: Elevated risk thresholds predict endocrine risk-reducing medication use in the Athena screening registry

Risk threshold

(1)

(2)

(3)

5-year risk ≥ 1.67%

5-year risk < 1.67%

Top 10% by age

Lower 90% by age

Top 2.5% by age

Lower 97.5% by age

Mean risk

5 year

Life

5 year

Life

5 year

Life

5 year

Life

5 year

Life

5 year

Life

Endocrine risk reduction

3.52%

15.90%

1.11%

7.82%

4.54%

21.71%

1.62%

8.22%

5.68%

27.73%

1.97%

9.74%

No endocrine risk reduction

2.54%

11.66%

1.02%

8.70%

3.31%

18.13%

1.30%

8.70%

5.06%

25.41%

1.41%

9.25%

  1. The mean 5-year and lifetime BCRAT risk for those who use endocrine risk-reducing medication and those that do not within the Athena Network registry for three risk thresholds: absolute risk ≥ 1.67, top 10% of risk by age, and top 2.5% of risk by age. The lifetime BCRAT risk is estimated to age 90. p < 0.001 for each threshold (1, 2, 3) using Pearson’s Chi-square test between thresholds and endocrine risk reduction use.