Table 3 Rates of 1-year treatment-related amenorrhea following common adjuvant chemotherapy regimens and overall by age.
From: Treatment-related amenorrhea in a modern, prospective cohort study of young women with breast cancer
Regimen | Age at diagnosis (years) | |||
|---|---|---|---|---|
≤30 | 31–35 | 36–40 | Overall | |
AC (+/−H, +/−P) | 2/3 (66.7%) | 2/15 (13.3%) | 6/22 (27.3%) | 10/40 (25.0%) |
AC-T(+/−H, +/−P) | 11/59 (18.6%) | 43/105 (41.0%) | 103/192 (53.6%) | 157/356 (44.1%) |
TC (+/−H, +/−P) | 5/18 (27.8%) | 7/16 (43.8%) | 16/33 (48.5%) | 28/67 (41.8%) |
TH | 0/5 (0%) | 0/2 (0%) | 3/20 (15.0%) | 3/27 (11.1%) |
TCH (+/−P) | 1/2 (50.0%) | 6/15 (40.0%) | 13/19 (68.4%) | 20/36 (55.6%) |
All regimens | 21/93 (22.6%) | 68/190 (35.8%) | 169/329 (51.4%) | 258/592 (43.6%) |
