Table 4 Rates of 2-year treatment-related amenorrhea following common adjuvant chemotherapy regimens and overall by age.
From: Treatment-related amenorrhea in a modern, prospective cohort study of young women with breast cancer
Regimen | Age at diagnosis (years) | |||
|---|---|---|---|---|
≤30 | 31–35 | 36–40 | Overall | |
AC (+/−H, +/−P) | 1/4 (25.0%) | 1/14 (7.1%) | 3/120 (2.5%) | 5/138 (3.6%) |
AC-T(+/−H, +/−P) | 5/60 (8.3%) | 19/97 (19.6%) | 43/172 (25%) | 67/329 (20.4%) |
TC (+/−H, +/−P) | 2/17 (11.8%) | 2/17 (11.8%) | 5/24 (20.8%) | 9/58 (15.5%) |
TH | 0/5 (0%) | 1/3 (33.3%) | 2/19 (10.5%) | 3/27 (11.1%) |
TCH (+/−P) | 0/1 (0%) | 1/14 (7.1%) | 3/17 (17.6%) | 4/32 (12.5%) |
All regimens | 10/93 (10.8%) | 27/160 (16.9%) | 65/286 (22.7%) | 102/539 (18.9%) |
