Table 1 Clinicopathologic characteristics of study cohort.

From: The incidence of discordant clinical and genomic risk in patients with invasive lobular or ductal carcinoma of the breast: a National Cancer Database Study

 

ILC (N = 1497)

IDC (N = 5902)

P Value

Age at diagnosis (years), mean (SD)

60.9 (10.4)

59.1 (11.1)

<0.001

Pathologic stage, n (%)

  

<0.001

 I

727 (48.6%)

3744 (63.4%)

 

 II

664 (44.4%)

1993 (33.8%)

 

 III

106 (7.1%)

165 (2.8%)

 

Tumor grade, n (%)

  

<0.001

 1

345 (23.1%)

1534 (26.0%)

 

 2

1022 (68.3%)

3137 (53.2%)

 

 3

130 (8.7%)

1231 (20.9%)

 

Clinical risk, n (%)

  

<0.001

 Low

719 (48.0%)

3362 (57.0%)

 

 High

778 (52.0%)

2540 (43.0%)

 

Genomic risk, n (%)

  

<0.001

 Low

1085 (72.5%)

3435 (58.2%)

 

 High

412 (27.5%)

2467 (41.8%)

 

Surgical therapy, n (%)

  

<0.001

 Lumpectomy

803 (53.6%)

4018 (68.1%)

 

 Mastectomy

694 (46.4%)

1884 (31.9%)

 

Adjuvant therapy, n (%)

   

 Chemotherapy

434 (29.5%)

2164 (37.4%)

<0.001

 Endocrine therapy

1375 (93.4%)

5270 (91.0%)

0.003

Charlson-Deyo Score, n (%)

  

0.434

 0

1287 (86.0%)

5052 (85.6%)

 

 1

177 (11.8%)

707 (12.0%)

 

 2

22 (1.5%)

114 (1.9%)

 

 ≥3

11 (0.73%)

29 (0.49%)

 
  1. ILC invasive lobular carcinoma, IDC invasive ductal carcinoma.