Fig. 5: Spatial characteristics of ER+HER2− breast cancer show prognostic value. | npj Breast Cancer

Fig. 5: Spatial characteristics of ER+HER2− breast cancer show prognostic value.

From: Spatial interplay of lymphocytes and fibroblasts in estrogen receptor-positive HER2-negative breast cancer

Fig. 5

a Univariate cox regression. Hazard ratios (HR) with 95% confidence intervals (CI) for the spatial measurements and clinical parameters for ER+HER2+ samples only (N = 603). P-values non-adjusted for multiple testing. b The multivariate cox regression for the significant univariate variables under a Hazard ratios (HR) with 95% confidence intervals (CI) on x-axis. c The overall survival probability of ER+HER2− tumors with a low \({{{{D}}}}_{{{{\mathrm{KL}}}}}({{{{P}}}}_{{{{\mathrm{Fibroblast}}}}}||{{{{P}}}}_{{{{\mathrm{TILs}}}}})\) (=mixed) and high \({{{{D}}}}_{{{{\mathrm{KL}}}}}({{{{P}}}}_{{{{\mathrm{Fibroblast}}}}}||{{{{P}}}}_{{{{\mathrm{TILs}}}}})\) (=restricted). P values under a and b are the result of the log likelihood ratio test.

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