Fig. 4: Gene activity signatures of FOXA1 and ER targets. | npj Breast Cancer

Fig. 4: Gene activity signatures of FOXA1 and ER targets.

From: GRHL2 motif is associated with intratumor heterogeneity of cis-regulatory elements in luminal breast cancer

Fig. 4: Gene activity signatures of FOXA1 and ER targets.The alt text for this image may have been generated using AI.

a, b Aggregated ATAC signal tracks around TSS (left), gene activity scores (center), and motif enrichment scores (right) of FOXA1 in a and ESR1 in b for each cancer cluster. c, d Aggregated ATAC signal tracks around TSSs of the represented targets (left) and signature scores (right) of genes targeted by FOXA1 in c, ER in d for each cancer cluster.

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