Fig. 3: PolySia and ST8Sia4 expression in tumor cells and tumor-infiltrating lymphocytes.

A and B Correlation between tumor cell (n = 93) (A) and (B) TIL (n = 70) polySia expression levels plotted relative to ST8Sia4 expression levels for each matched tissue core. Gray line = Regression line. Pearson correlation test and simple linear regression test. C–E Representative images of polySia and ST8Sia4 expression serial sections. Zooms are of similar regions for each matched set. Arrows point to tumor cells (black arrows) and lymphocytes (red arrows) positive for polySia and/or ST8Sia4. Scale bar = 200 µm (cores) and 50 µm (insets).