Fig. 5: PolySia and CD56 expression in primary breast tumors. | npj Breast Cancer

Fig. 5: PolySia and CD56 expression in primary breast tumors.

From: The different prognostic significance of polysialic acid and CD56 expression in tumor cells and lymphocytes identified in breast cancer

Fig. 5: PolySia and CD56 expression in primary breast tumors.The alternative text for this image may have been generated using AI.

A–C Immunohistochemical staining of polySia (top row) and CD56 (bottom row) in each panel in breast cancer tissue. Representative images are shown alongside higher magnification insets from the same core. Arrows point to clusters of cells positive for polySia and CD56. Representative images are shown alongside higher magnification insets from the same core. Scale bar = 200 µm (cores), or 50 µm (insets). D Correlation between polySia expression levels plotted relative to CD56 expression levels for each matched tissue core (n = 32; gray line: regression line). Pearson correlation test and simple linear regression test. E Correlation matrix of all clinical data and polySia and CD56 expression (n = 32). Color map represents correlation strength between each data set; represented as positive (blue) or negative (red). Pearson R values are indicated in each box. F PolySia expression levels categorized based on disease specific patient outcome (Alive [n = 19], Deceased [n = 13]). ±SEM, unpaired t-test.

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