Fig. 4: Copy number aberration analysis in the bulk tumor and in CTCs.
From: Interrogating breast cancer heterogeneity using single and pooled circulating tumor cell analysis
a Clustering of all CTCs and bulk tumors, showing that samples cluster by patient. b–d Plot of the copy number by chromosome for all samples in patient #1, triple-negative (b), patient #2, HER2 positive (c) and patient #3 ER+/HER2− (d). Non-segmented estimates are given in light gray to show the estimate variance. ER Estrogen receptor, HER2 Human epidermal growth factor receptor 2.
