Fig. 2: The allograft rejection score was strongly correlated with infiltration of immune cells. | npj Breast Cancer

Fig. 2: The allograft rejection score was strongly correlated with infiltration of immune cells.

From: Enhanced immune response outperform aggressive cancer biology and is associated with better survival in triple-negative breast cancer

Fig. 2

a Scatter plots between allograft rejection score and the fraction of anti-cancer immune cells; CD8+ T cells, CD4+ memory T cells, type1 T helper (Th1) cells, M1 macrophages, and pro-cancer immune cells; regulatory T cells (Tregs), type 2 T (Th2) cells, M2 macrophages, and B cells, calculated by xCell algorithm, in the METABRIC and GSE96058 cohorts. b Correlation plots between allograft rejection score and expression of immune checkpoint molecules, including PDCD1/PD-1, CD274/PD-L1, PDCD1LG2/PD-L2, CTLA4, LAG3, TIGIT, BTLA, and HLA-A in both cohorts. Spearman rank correlation was used for the analysis. *p < 0.01, **p = 0.13, ***p = 0.91.

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