Fig. 3: T6Is differentially affect ERα lifetime in breast cancer cells. | npj Breast Cancer

Fig. 3: T6Is differentially affect ERα lifetime in breast cancer cells.

From: Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells

Fig. 3: T6Is differentially affect ERα lifetime in breast cancer cells.

a In-cell Western of endogenous ERα levels normalized to cell count in T47D breast cancer cells. b Summary of halo-ERα accumulation at maximum dose (1 μM). c Representative dose-response of halo-ERα expression in T47D breast cancer cells, data are normalized to cell count in their respective wells. All data are shown as the mean of three replicates ± s.d., ns = not significant, *p < 0.05, ***p < 0.0005 by unpaired t test. Error bars represent s.d.

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