Fig. 5: T6Is are effective anti-proliferative agents in ER+, hormone-dependent, breast cancer cells. | npj Breast Cancer

Fig. 5: T6Is are effective anti-proliferative agents in ER+, hormone-dependent, breast cancer cells.

From: Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells

Fig. 5: T6Is are effective anti-proliferative agents in ER+, hormone-dependent, breast cancer cells.

T47D (a) and MCF7 (b) cell count after 7 days of treatment in the presence of 1 nM E2, data are the mean ± s.d. for three replicates normalized to vehicle. c Crystal violet viability assay of MCF7 breast cancer cells treated in the presence of 1 nM E2, data are the mean of 3 replicates ± s.d. and are normalized to 1 nM E2. Significance determined by unpaired t test where *p < 0.05, ****p < 0.00005. Error bars represent s.d.

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