Fig. 9: T6I-29-1A shows reduced ERα target gene downregulation compared to ICI, Laso, and RAD1901. | npj Breast Cancer

Fig. 9: T6I-29-1A shows reduced ERα target gene downregulation compared to ICI, Laso, and RAD1901.

From: Unconventional isoquinoline-based SERMs elicit fulvestrant-like transcriptional programs in ER+ breast cancer cells

Fig. 9: T6I-29-1A shows reduced ERα target gene downregulation compared to ICI, Laso, and RAD1901.The alt text for this image may have been generated using AI.

Data are the mean of 3 replicates ± s.d. Error bars represent s.d. ΔΔCt = ΔCt(drug + E2) – ΔCt(E2). Significance determined by unpaired t test where **p < 0.005, ***p < 0.0005, ****p < 0.00005, ns = not significant.

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