Fig. 1: Restricted cubic splines describing the non-linear association between BMI and pCR among neoadjuvant targeted therapy treated HER2 positive breast cancer patients.

Odds ratios are based on Logistic regression adjusted for age, clinical T stage, hormone receptor, HER2 staining intensity, Ki67, and neoadjuvant targeted therapy. The dotted lines represent the 95% confidence intervals for the spline model.