Table 1 Patient characteristics by BMI categories.

From: Impact of body mass index in therapeutic response for HER2 positive breast cancer treated with neoadjuvant targeted therapy: a multi-center study and meta-analysis

Characteristics

Overall (n = 491)

BMI categories

P valuea

Under-/normal weight

Overweight/obesity

(n = 299)

(n = 192)

Age (years)

   

0.002

 <49

239

162

77

 ≥49

252

137

115

Menopausal status

   

0.098

 Premenopausal

291

188

103

 Postmenopausal

195

109

86

 Unknown

5

2

3

Clinical T stage

   

0.104

 T1-2

372

219

153

 T3-4

119

80

39

Nodal status

   

0.452

 Negative

111

71

40

 Positive

380

228

152

Hormone receptor

   

0.132

 Negative

240

138

102

 Positive

251

161

90

HER2 staining intensity

   

0.425

 2+

40

22

18

 3+

451

277

174

Ki67 (%)

   

0.943

 <40

203

124

79

 ≥40

288

175

113

Neoadjuvant targeted therapy

   

0.676

 Trastuzumab

358

216

142

 Trastuzumab plus Pertuzumab

133

83

50

Pathological response

   

0.008

 Non-pCR

302

170

132

 pCR

189

129

60

  1. aP-values were calculated using the two-tailed χ2 test.