Table 2 Multivariate analysis of the association between BMI categories and pCR.
Characteristics | Adjusted multivariate analysis | ||
|---|---|---|---|
OR | 95%CI | P valuea | |
Age (years) | |||
<49 | 1 | – | – |
≥49 | 1.52 | 1.015–2.278 | 0.042 |
BMI categories | |||
Under-/normal weight | 1 | – | – |
Overweight/obesity | 0.497 | 0.328–0.753 | 0.001 |
Clinical T stage | |||
T1-2 | 1 | – | – |
T3-4 | 0.663 | 0.411–1.069 | 0.092 |
Hormone receptor | |||
Negative | 1 | – | – |
Positive | 0.359 | 0.240–0.538 | <0.001 |
HER2 | |||
2+ | 1 | – | – |
3+ | 2.513 | 1.023–6.174 | 0.045 |
Ki67 (%) | |||
<40 | 1 | – | – |
≥40 | 1.303 | 0.871–1.949 | 0.198 |
Neoadjuvant targeted therapy | |||
Trastuzumab | 1 | – | – |
Trastuzumab plus Pertuzumab | 2.397 | 1.547–3.715 | <0.001 |
