Table 2 Breast MRI features of pathologically confirmed HLBC.

From: Defining features of hereditary lobular breast cancer due to CDH1 with magnetic resonance imaging and tumor characteristics

Feature

Women with ILC and breast MRI dataa (n = 18)

Sizeb, median [Q1–Q3], cm

5.0 [2.1–7.4]

Discrete mass, n (%)

14/18 (77.8)

Shape

14/14 (100.0)

 Round, n (%)

2/14 (14.3)

 Irregular, n (%)

11/14 (78.5)

 Otherc, n (%)

1/14 (7.1)

Margin, n (%)

13/14 (92.9)

 Circumscribed, n (%)

2/13 (15.4)

  Round, n (%)

1/2 (50.0)

  Irregular, n (%)

1/2 (50.0)

 Non-circumscribed, n (%)

11/13 (84.6)

  Irregular, n (%)

6/11 (54.5)

  Spiculated, n (%)

5/11 (45.5)

Internal enhancement, n (%)

13/14 (92.9)

 Homogenous, n (%)

8/13 (61.5)

 Heterogeneous, n (%)

5/13 (38.5)

Non-mass enhancement, n (%)

15/17 (88.2)

Distribution, n (%)

15/15 (100.0)

 Regional, n (%)

8/15 (53.3)

 Focal, n (%)

5/15 (33.3)

 Linear, n (%)

1/15 (6.7)

 Multiple regions, n (%)

1/15 (6.7)

Internal enhancement, n (%)

15/15 (100.0)

 Homogenous, n (%)

0/15 (0.0)

 Heterogeneous, n (%)

3/15 (20.0)

 Clumped, n (%)

12/15 (80.0)

Associated features, n (%)

5/18 (27.8)

 Skin or nipple retraction, n (%)

3/5 (60.0)

 Axillary adenopathy, n (%)

3/5 (60.0)

 Architectural distortion, n (%)

2/5 (40.0)

  1. HLBC hereditary lobular breast cancer, IQR interquartile range.
  2. aWomen with ILC who had breast MRI available for radiographic assessment
  3. bSize of largest single dimension based on MRI assessment
  4. cToo small to characterize (obscured by clip).