Table 1 Demographics, clinical features and treatments received in MBC patients by socioeconomic status and race.
From: Effects of socioeconomic status and race on survival and treatment in metastatic breast cancer
Low SES (N = 832) | High SES (N = 414) | P-val | Black (N = 100) | White (N = 1111) | P-val | |
|---|---|---|---|---|---|---|
Age, mean(SD) | 56.1 [12.8] | 57.6 [13.0] | 0.049 | 56.4 [12.4] | 56.6 [13.0] | 0.89 |
Race (Black, %) | 10.5 | 3.7 | <0.001 | NA | NA | NA |
Missing (N) | 22 | 13 | NA | NA | ||
Histology (D, L in %) | 80, 10 | 76, 12 | 0.5 | 77, 9.3 | 79, 10.7 | 0.39 |
Missing (N) | 55 | 25 | 3 | 73 | ||
Denovo mets, Yes N,% | 182, 21.9 | 93, 22.5 | 0.87 | 23, 23% | 244, 22% | 0.9 |
Subtype (%) | ||||||
ER + /HER2+ | 12.3 | 17.6 | 0.1 | 9.4 | 14.3 | 0.13 |
ER-/HER2+ | 8.9 | 8.1 | 4.2 | 9.1 | ||
ER + /HER2- | 56.8 | 53.9 | 59.4 | 55.3 | ||
ER-/HER2- (Triple Negative) | 22 | 20.4 | 27.1 | 21.3 | ||
Missing (N) | 45 | 21 | 4 | 55 | ||
Number of metastases, median [IQR] | 3 [2–4] | 3 [2–4] | 0.84 | 3 [2–4] | 3 [2–4] | 0.9 |
Visceral metastases at diagnosis, Yes % | 39 | 41 | 0.7 | 40 | 40 | >0.99 |
Missing (N) | 0 | 1 | 0 | 0 | ||
Utilization of different treatment options in MBC | ||||||
Chemotherapy in all MBC (Yes %) | 83 | 83 | 0.99 | 77 | 83 | 0.12 |
Missing (N) | 5 | 2 | 1 | 2 | ||
Chemotherapy in Triple negative MBC (Yes %) | 93 | 97.5 | 0.25 | 92.3 | 94 | 0.96 |
Missing (N) | 0 | 1 | 0 | 0 | ||
Lines of chemotherapy in MBC, Median[IQR] | 2 [1,4] | 3 [1–5] | 0.19 | 2 [1,3] | 3 [1,5] | 0.03 |
Missing (N) | 5 | 2 | 1 | 2 | ||
Lines of chemotherapy in Triple negative MBC, Median[IQR] | 3 [2–5] | 3 [2–5] | .37 | 3 [2.4] | 3 [2,5] | 0.9 |
Missing (N) | 0 | 1 | 0 | 0 | ||
HER2 targeted therapy in HER2 + patients (Yes %) | 90 | 87 | 0.34 | 85 | 89 | >0.99 |
Missing (N) | 2 | 0 | 1 | 1 | ||
Hormone therapy in ER + patients (Yes %) | 91 | 91 | 0.9 | 94 | 91 | 0.29 |
Missing (N) | 3 | 0 | 1 | 1 | ||
Tamoxifen use in first line hormone therapy in ER + patients (Yes %) | 18 | 13 | 0.07 | 18 | 16.7 | 0.97 |
Missing (N) | 70 | 38 | 7 | 97 | ||