Fig. 1: Histopathological growth pattern (HGP) in BCLM patients. | npj Breast Cancer

Fig. 1: Histopathological growth pattern (HGP) in BCLM patients.

From: Histopathological growth patterns and tumor-infiltrating lymphocytes in breast cancer liver metastases

Fig. 1

a Hematoxylin and eosin (H&E) sections of desmoplastic liver metastasis at magnification ×2 (left), ×10 (middle) and schematic illustration (right) of the desmoplastic pattern with the desmoplastic rim between the hepatocytes and the cancer cells. b H&E sections of replacement liver metastasis at magnification ×2 (left), ×10 (middle) and schematic illustration of the replacement HGP (right) with direct contact between the hepatocytes and the cancer cells. c Proportion (%) of patients (n = 133) from the surgical cohort per HGP categories. ‘Any d-HGP’ (blue) and ‘pure r-HGP’ (red). d HGP distribution (%) in the 133 patients from the surgical cohort. e Proportion (%) of patients from the post-mortem cohort (n = 23) per HGP categories. ‘Any d-HGP’ (blue) and ‘pure r-HGP’ (red). f HGP distribution (%) in the 23 patients from the post-mortem cohort. Blue= desmoplastic, red= replacement, green= pushing. H&E Hematoxylin & Eosin, HGP Histopathological Growth Pattern, d Desmoplastic, r Replacement.

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