Table 2 Median and interquartile ranges of baseline and absolute changes in adipokines, insulin, and HOMA index by BMI stratification (non-obese and obese).

Leptin (L) baseline (ng/mL)

29.2 (18.6; 36.6)

80 (47.6; 104.8)

28.7 (14.4; 44.7)

73.8 (59.0; 82.4)

27.9 (14.2;38.5)

78.6 (63.1; 98.0)

0.715

0.574

0.523

0.978

Leptin absolute change

−5.8 (−10.9; −2.5)

−10.9 (−31.2; −1.1)

0 (−8.3; 2.9)

−12.6 (−20.5; −5.3)

−1.4 (−5; 4.4)

−4.5 (−13.2; 7.6)

0.015

0.047

0.739

0.066

Adiponectin (A) baseline (µg/mL)

12.1 (10.2;15.0)

8.0 (4.8; 11.8)

8.8 (6.7;11.9)

7.3 (5.2; 11.5)

8.6 (6.5; 12.9)

0.005

0.013

0.831

0.629

0.005

Adiponectin absolute change

−1.36 (−2.32; 0.3)

−0.86 (−1.71; −0.2)

−0.26 (−0.9; 0.76)

−0.06 (−0.54; 0.34)

−0.16 (−1.00; 0.69)

0.01 (−0.40; 0.67)

0.030

0.554

0.049

0.006

A/L ratio absolute change

0.049 (−0.013; 0.187)

0.016 (−0.011; 0.064)

−0.013 (−0.060; 0.058)

0.020 (−0.001; 0.060)

0.003 (−0.093; 0.049)

0.000 (−0.029; 0.034)

0.045

0.110

0.749

0.118

Insulin baseline (uU/mL)

7.1 (5.7; 10.6)

8.4 (5.9; 11.4)

7.6 (5.9; 10.9)

11.6 (6.5; 17.8)

8.0 (4.8; 11.0)

7.0 (6.7; 13.1)

0.626

0.874

0.252

0.807

Insulin absolute change

0.2 (−1.3; 3.7)

0.6 (−0.7; 3.3)

0.7 (−1.1; 3.1)

0.6 (−1.3; 3.2)

0.4 (−1.1; 1.9)

−0.2 (−5.8; 3.5)

0.617

0.671

0.459

0.687

HOMA baseline

1.5 (1.3; 2.6)

2.1 (1.5; 3.0)

1.9 (1.4; 2.8)

3.4 (1.6; 6.2)

2.0 (1.2; 2.8)

1.7 (1.4; 3.6)

0.359

0.800

0.239

0.957

HOMA absolute change

0.08 (−0.37; 0.90)

0.40 (−0.47; 1.26)

0.08 (−051; 0.63)

0.50 (−0.76; 1.52)

0.08 (−0.44; 1.00)

0.10 (−0.98; 0.81)

0.732

0.186

0.363

0.796