Fig. 3: Comparative analysis of immune signature expression through supervised gene expression analysis between day 14 samples and surgery tumor specimens, categorized by different treatment arms.

The numerical values correspond to Fold Change, computed using a two-class paired Significance Analysis of Microarrays (SAM), highlighting alterations. Color-coded boxes identify modules exhibiting significant changes with a false discovery rate (FDR) of ≤ 0.05, with upregulation in red and downregulation in green.