Table 1 Correlation of USP4 and BRCA1 expression in breast cancer

From: The deubiquitinating enzyme USP4 regulates BRCA1 stability and function

USP4 protein level

BRCA1 protein level

P value

−/+

++

+++

Total

−/+

102 (45.1)

33 (14.6)

8 (3.5)

143 (63.2)

p < 0.0001

++

28 (12.4)

30 (13.3)

7 (3.1)

65 (28.8)

+++

4 (1.8)

6 (2.7)

8 (3.5)

18 (8.0)