Table 3 Treatment-related adverse events

From: Clinical impact of drug-drug interactions on abemaciclib in the real-world experience of AB-ITALY study

Adverse events

N (%)

Adverse event, any

Yes

133 (77)

No

40 (23)

Dose reduction, any

Yes

56 (32)

No

117 (68)

Diarrhea

 

Any grade

109 (62)

Grade 3/4

8 (4)

Neutropenia

 

Any grade

85 (49)

Grade 3/4

18 (10)

Ashtenia

 

Any grade

85 (49)

Grade 3/4

4 (2)

Anemia

 

Any grade

62 (36)

Grade 3/4

5 (3)

Nausea

 

Any grade

15 (8)

Grade 3/4

1 (0)

Hepatotoxicity

 

Any grade

14 (7)

Grade 3/4

3 (1)

Renal toxicity

 

Any grade

35 (19)

Grade 3/4

1 (0)

DVT/pulmunary embolism

Yes

6 (3)

No

167 (97)

  1. N number of patients, DVT deep vein thrombosis.
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