Table 2 Chemotherapies at study entry independent from therapy lines according to genomic BRCA (gBRCA) mutation and hormone receptor (HR) status (N = 471)

From: Susceptibility gene mutations in germline and tumors of patients with HER2-negative advanced breast cancer

Chemotherapy

gBRCA mutation status

Hormone receptor status

Mutation (N = 23)

Wildtype (N = 448)

Positive (N = 388)

Negative (N = 76)

Anthracyline taxane combination

2 (8.7)

32 (7.1)

32 (8.2)

1 (1.3)

Anthracycline monotherapy

1 (4.3)

56 (12.5)

56 (14.4)

0 (0.0)

Taxane monotherapy

6 (26.1)

100 (22.3)

88 (22.7)

16 (21.1)

Bevacizumab treatments

4 (17.4)

106 (23.7)

89 (22.9)

20 (26.3)

Platinum-based therapy

8 (34.8)

47 (10.5)

30 (7.7)

24 (31.6)

Eribulin

1 (4.3)

31 (6.9)

20 (5.2)

11 (14.5)

Capecitabine monotherapy

1 (4.3)

45 (10.0)

43 (11.1)

3 (3.9)

Capecitabine taxane combination

0 (0.0)

7 (1.6)

7 (1.8)

0 (0.0)

Vinorelbine monotherapy

0 (0.0)

11 (2.5)

11 (2.8)

0 (0.0)

Other

0 (0.0)

13 (2.9)

12 (3.1)

1 (1.3)

  1. Treatment patterns for number of cycles per line, schedules, durations and reason for discontinuation are not available. Data is presented as N (%)