Table 3 Adjusted association with time to death from Landmarks post 1st stereotactic radiosurgery
Patient Characteristics | Hazard Ratio | 95% CI | P-value |
|---|---|---|---|
Landmark 1 | |||
Systemic PD prior to LM1 vs not. | 4.28 | 1.98, 9.12 | 0.0002 |
Age (per decade) | 0.82 | 0.63, 1.06 | 0.1264 |
Race (white vs not white) | 0.96 | 0.38, 2.43 | 0.9257 |
KPS 90–100 vs <90 | 0.52 | 0.26, 1.01 | 0.0537 |
ER + /Her2- vs Her2+ | 2.08 | 1.01, 4.25 | 0.0456 |
ER-/Her2- vs Her2+ | 2.28 | 0.92, 5.60 | 0.0736 |
Brain Mets at SRS1 ( > 1 vs 1) | 1.92 | 1.01, 3.62 | 0.0455 |
PTV (per log) | 1.02 | 0.83, 1.26 | 0.8504 |
Fractions (1 vs 3 or 5) | 1.14 | 0.55, 2.36 | 0.7206 |
Landmark 2 | |||
Systemic PD prior to LM2 vs not. | 7.40 | 3.10, 17.63 | <0.0001 |
Age (per decade) | 0.87 | 0.66, 1.14 | 0.3004 |
Race (white vs not white) | 0.56 | 0.21, 1.50 | 0.2451 |
KPS 90–100 vs <90 | 0.55 | 0.26, 1.18 | 0.1267 |
ER + /Her2- vs Her2+ | 1.23 | 0.57, 2.66 | 0.5966 |
ER-/Her2- vs Her2+ | 1.06 | 0.38, 2.95 | 0.9095 |
Brain Mets at SRS1 ( > 1 vs 1) | 1.59 | 0.78, 3.25 | 0.2066 |
PTV (per log) | 1.15 | 0.90, 1.46 | 0.2625 |
Fractions (1 vs 3 or 5) | 1.22 | 0.54, 2.78 | 0.6366 |
