Table 2 Estradiol, estrone, and FSH levels at 1 year, overall and according to oral endocrine therapy

From: Estrogen levels in young women with hormone receptor-positive breast cancer on ovarian function suppression therapy

Hormone

Median (range)

P

Overall (N = 84)

Tamoxifen (N = 59)

AI (N = 25)

E2 (pg/mL)

3.0 ( < 0.2*–30.9)

3.9 (1.0–19.6)

2.1 ( < 0.2*–30.9)

0.001

E1 (pg/mL)

10.0 ( < 0.2*–43.4)

13.3 (0.2*–43.4)

1.4 ( < 0.2*–29.0)

< 0.001

FSH (IU/L)

3.3 (1.2–87.7)

2.5 (1.2–84.4)

7.1 (2.4–87.7)

< 0.001

  1. *Estrogen concentrations below lower limit of quantification ( < 1 pg/mL) for assay have an accuracy of ± 50%.
  2. E2 estradiol, E1 estrone, FSH follicle stimulating hormone.
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