Fig. 3: Gene expression analysis to identify upregulated and down regulated genes.

A Changes in gene expression at post-NAC evaluation compared to baseline. B Changes in gene expression at surgery evaluation compared with the post-NAC. Colored dots mark upregulated and downregulated genes with a false discovery rate <5%. Names are reported for the differentially expressed genes. Post-NAC Post neoadjuvant treatment but before starting treatment with palbociclib.