Fig. 2: Radiographic responses to CNS metastases of metastatic breast cancer with SG.

Baseline and Central Nervous system (CNS) response assessment by MRI Brain imaging of patients with metastatic breast cancer patients with CNS metastases treated with sacituzumab govitecan. LMD: leptomeningeal disease;BM: Brain Metastases. Patient #11 with stable BM received RT (SRS) less than two months before the initiation of OS. Patient #27 was irradiated for 9 months on another lesion (temporal) and patient #31 did not receive any irradiation before the SG.