Table 6 Cox prognostic models for TILs and OS for the cohort of patients whose TILs were evaluated at the metastatic site (=57 patients)
Variable | Univariate HR (95% CI) | p-Value | Variable | Adjusted HR (95% CI) | p-Value |
|---|---|---|---|---|---|
Age (continuous) | 0.98 (0.94-1.03) | 0.386 | Age (continuous) | 0.99 (0.95-1.05) | 0.937 |
Visceral disease | Visceral disease | ||||
No | Reference | No | Reference | ||
Yes | 1.34 (0.47-3.78) | 0.583 | Yes | 4.89 (1.08-22.0) | 0.039 |
Site of Metastasis | Site of Metastasis | ||||
Lung | Reference | Lung | Reference | ||
Liver | 1.22 (0.24-6.29) | 0.816 | Liver | 0.87 (0.12-6.24) | 0.889 |
Bone | 3.26(0.63-16.93) | 0.161 | Bone | 5.55 (0.61-50.76) | 0.129 |
Lymph node | 1.96 (0.36-10.76) | 0.438 | Lymph node | 1.46 (0.21-10.20) | 0.702 |
Soft Tissue | 1.16(0.16-8.34) | 0.880 | Soft Tissue | 1.87 (0.21-16.86) | 0.575 |
HR | HR | ||||
Negative | Reference | Negative | Reference | ||
Positive | 2.44 (0.91-6.51) | 0.076 | Positive | 2.04 (0.67-6.16) | 0.206 |
TILs | TILs | ||||
High (>5%) | Reference | High (>5%) | Reference | ||
Low (≤5%) | 3.18 (1.19- 8.50) | 0.021 | Low (≤5%) | 2.97 (0.90-9.87) | 0.075 |
