Fig. 3: Temporal dynamics of monocytes and B cell during treatment. | npj Breast Cancer

Fig. 3: Temporal dynamics of monocytes and B cell during treatment.

From: Dynamic single-cell systemic immune responses in immunotherapy-treated early-stage HR+ breast cancer patients

Fig. 3

A Umap visualization of major monocyte clusters, with representative markers depicted by dotplot. B Differential gene expression analysis performed on total monocytes between RCB0/I and RCB II/III patients at baseline. C ssGSEA interferon response score calculated for individual monocytes, t-test was performed. D B cell abundance compared longitudinally, a paired T-test was performed. E Differential gene expression analysis was performed on total B cells between RCB0/I and RCB II/III patients at baseline. F Differential gene expression analysis performed on total B cells between RCB0/I and RCB II/III patients post-chemotherapy. For all volcano plots, Log2 fold change cutoff at 0.5, padj cutoff at 1e-5.

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