Fig. 5: Genetic alterations in homologous recombination deficiency/DNA damage repair genes in breast cancer according to age.
From: Genomic landscape of breast cancer in elderly patients

Frequency of germline and somatic genetic alterations in homologous recombination deficiency (HRD)/DNA damage response (DDR) genes in elderly, middle-aged and young patients (a), and proportion of mono- and bi-allelic inactivation in HRD/DDR-altered cases according to age (b). Analysis includes all breast cancer samples regardless of sample type or ER/HER2 status. n.s. non-significant; Fisher’s exact test.