Table 2 Significance (p value) of the fatty acids and lipid indexes of the early-stage breast cancer (BC) patients of this study compared among BMI groups [normal weight, NW (BMI = 18.5–24.9) n = 26; overweight, OW (BMI = 25–29.9) n = 11; obese, OB (BMI = 30–39.9) n = 13] and to the healthy normal weight control group (Healthy, n = 41)

From: Use of membrane lipidome, body weight, and composition in stratification of early breast cancer patients

Fatty acids and Indexes

BC NW

vs

Healthy

p value

BC OW

vs

Healthy

p value

BC OB vs Healthy p value

BC OB vs

BC NW

p value

C16:0 palmitic acid

0.0010

-

-

0.011

9c-C16:1 palmitoleic acid

0.0068

-

-

-

C18:0 stearic acid

0.0017

0.014

-

-

C20:3 omega-6 (dihomo-gamma linolenic acid)

-

0.002

-

-

C20:4 omega-6 (arachidonic acid)

0.0002

0.025

0.0093

-

C20:5 omega-3 (eicosapentaenoic acid)

0.02

-

-

-

SFA

≤0.0001

0.0049

-

0.0038

PUFA

≤0.0001

0.03

-

0.023

PUFA omega-6

0.0002

0.02

-

-

SFA/MUFA

0.05

-

-

-

Saturation index (b)

0.03

-

-

-

Delta-6desaturase+elo index

-

-

0.03

-

Unsaturation index UI

≤0.0001

-

-

0.04

Peroxidation index PI

0.004

-

-

-

  1. Full data are reported in Supplementary Table 3, and corresponding graphs are shown in Fig. 3.