Fig. 3: A 50-gene transcriptomic signature (TS) distinguishes the high-risk patients with poor overall survival (OS) in the SCAN-B cohort.

A Kaplan–Meier survival analysis discriminates patients with high risk of death (red) based on TS (Log-rank test, p = 0.032). B Both (i) univariate and (ii) multivariate Cox proportional hazard regression analyses demonstrate that high risk for death as assessed by TS (TS-High) and stage are independent predictors of poor OS, even while adjusting for clinical variables (age, tumor stage, grade, Ki67). HR Hazard Ratio, CI Confidence Interval.