Fig. 6: Association of immune cell abundance with BC metastasis in subtype and race.

A Relative abundance of TAM in total BC, non-TNBC and TNBC samples, showing the metastatic tumors had significantly higher abundance of TAMs. B Relative abundance of T-cells in total BC, non-TNBC, and TNBC samples, showing the lower abundance of T-cells was significantly associated with metastasis in non-TNBC samples but not in TNBC samples. C Relative abundance of CD8+ T-cells in total BC, non-TNBC and TNBC samples, showing a trend for lower CD8+ T-cells abundance in non-TNBC tumors was associated with metastasis. D Relative abundance of total immune cells (CD45), T-cells, DC, and NK-cells in White and Black samples, showing their association with metastasis. The p-value was calculated using the non-parametric Mann–Whitney test. A p-value < 0.05 was considered statistically significant.