Fig. 3: Differentially expressed genes and related pathways in TNBC patients.
From: Race-related host and microbe transcriptomic signatures in triple-negative breast cancer
(a) Volcano plot showing the log2 fold change and adjusted p-values for all differentially expressed genes between AA and EA cohorts (ā|ālog2FoldChangeā|āā„ā1, padjā<ā0.05). b, c Bar charts depicting canonical pathways predicted to be differentially activated in AA (red) versus EA (cyan), and MD-Cluster 1 (violet) vs MD-Cluster 2 (bright blue), respectively. Pathways were identified based on a Z-score cutoff of Ā±2 and a p-value of <0.05. Detailed lists of genes and pathways are available in Supplementary Data 2, 3. d, e Box plots of the xCell scores for preadipocytes by MD-Cluster and Th1 cells by race, respectively.
