Table 1 Characteristics of participants with up to 10 years of follow-up for the in-house dataset and the CSAW-CC dataset
From: Predicting short- to long-term breast cancer risk from longitudinal mammographic screening history
In-house dataset | |||
|---|---|---|---|
Characteristic | Cancer free,a N = 34,769 | Cases, a N = 8023 | P value b |
Age, years, mean (SD) | 53.77 (11.79) | 56.18 (11.68) | <0.01 |
Age at menarche, years, mean (SD) | 12.98 (3.81) | 12.87 (1.40) | 0.67 |
Menopausal status n/N(%) | <0.01 | ||
Pre-menopausal | 5333 (15.34%) | 944 (11.77%) | |
Peri-menopausal & Unknow | 17,825 (51.27%) | 3566 (44.45%) | |
Post-menopausal | 11,611 (33.39%) | 3513 (43.79%) | |
Family history of breast cancer, n/N(%) | 24,026 (69.10%) | 6852 (85,40%) | <0.01 |
Family history of ovarian cancer, n/N(%) | 2009 (5.78%) | 510 (6.36%) | 0.052 |
Breast density n/N(%) | <0.01 | ||
ACR 1 | 2250 (6.49%) | 445 (5.63%) | |
ACR 2 | 20,051 (57.83%) | 4941 (62.51%) | |
ACR 3 | 9385 (27.07%) | 1845 (23.34%) | |
ACR 4 | 2987 (8.61%) | 673 (8.61%) | |
Race n/N(%) | <0.01 | ||
White | 10,133 (29.14%) | 2133 (26.59%) | |
African | 135 (0.39%) | 25 (0.31%) | |
Asian | 265 (0.76%) | 31 (0.39%) | |
Other Race | 90 (0.26%) | 16 (0.20%) | |
Unknow | 24,146 (69.45%) | 5818 (72.52%) | |
Gene mutation (BRCA1/2, Tp53, Chek2) n/N(%) | 31 (0.09%) | 251 (3.13%) | 0.031 |
Personal history of breast cancer, n/N(%) | 17,711 (50.94%) | 4276 (53.30%) | <0.01 |
Personal history of ovarian cancer, n/N(%) | 368 (1.06%) | 138 (1.72%) | <0.01 |
Time to cancer, years n/N(%) | - | ||
0–1 | - | 3742 (46.64%) | |
1–2 | - | 719 (8.96%) | |
2–3 | - | 691 (8.61%) | |
3–4 | - | 593 (7.39%) | |
4–5 | - | 525 (6.54%) | |
5–6 | - | 451 (5.62%) | |
6–7 | - | 426 (5.31%) | |
7–8 | - | 351 (4.37%) | |
8–9 | - | 292 (3.64%) | |
9–10 | - | 233 (2.90%) | |
CSAW-CC dataset | |||
|---|---|---|---|
Characteristic | Cancer free,a N = 22,871 | Cases,aN = 1826 | Pvalue b |
Age range n/N(%) | <0.01 | ||
40–55 | 12,647 (55.30%) | 737 (40.36%) | |
>55 | 10,224 (44.70%) | 1089 (59.64%) | |
Percent mammographic density, mean (SD) | 24.25 (15.04) | 24.86 (14.95) | <0.01 |
Time to cancer n/N(%) | - | ||
0–60 days | - | 524 (28.70%) | |
60 days–2 years | - | 267 (14.62%) | |
2–7 years | - | 1035 (56.68%) | |
