Fig. 6: Multivariable analysis of risk factors for distant recurrence, adjusting for clinicopathologic variables in the first ten years. | npj Breast Cancer

Fig. 6: Multivariable analysis of risk factors for distant recurrence, adjusting for clinicopathologic variables in the first ten years.

From: Racial disparity in pro-metastatic tumor microenvironment in treatment naïve breast cancer

Fig. 6: Multivariable analysis of risk factors for distant recurrence, adjusting for clinicopathologic variables in the first ten years.

a Forest Plot of multivariable logistic regression modeling odds of distant recurrence in ER + /HER2- over first 10 years, adjusting for clinicopathological variables. b Forest Plot of multivariable logistic regression with interaction between race and high TMEM doorway score. Black patients with high TMEM Doorway scores had significantly higher odds of distant recurrence after adjustment for other clinicopathologic variables. White patients with high TMEM doorway scores were less likely to experience higher odds of distant recurrence compared to white patients with low TMEM doorway scores after adjusting for age, BMI, tumor size, lymph node status, grade, and treatment.

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