Table 2 Linear regression of mammogram risk score on each breast cancer risk factor

Risk factor^a	Crude model^b				Model adjusted for predicted BI-RADS density^c
Risk factor^a	N	BETA	SE	P	N	BETA	SE	P
Early life body size	837	−0.082	0.032	9.59×10⁻³	770	−0.022	0.032	0.479
Body mass index	849	−0.082	0.032	1.11×10⁻²	781	0.049	0.035	0.165
Waist-to-hip ratio	728	−0.059	0.034	0.085	668	−0.006	0.035	0.868
Waist-to-hip ratio adjusted for BMI	725	−0.006	0.034	0.869	665	0.008	0.034	0.807
Height	853	−0.024	0.032	0.440	785	−0.011	0.031	0.720
Age at menarche	850	0.003	0.032	0.922	782	−0.016	0.032	0.619
Age at first birth	699	0.031	0.035	0.384	649	0.037	0.034	0.277
Age at natural menopause^d	535	0.075	0.042	0.074	489	0.059	0.041	0.152
Postmenopausal hormone use^d	518	0.139	0.094	0.139	475	0.022	0.093	0.815
No. pregnancies ≥6 months	761	−0.005	0.033	0.876	722	0.029	0.033	0.387
History of benign breast disease	853	0.229	0.065	4.50 × 10⁻⁴	785	0.111	0.065	0.091
Predicted BI-RADS density	785	0.314	0.033	1.94 × 10⁻²⁰	-	-	-	-
Family history of breast cancer	853	0.017	0.081	0.838	785	0.003	0.080	0.974

BMI body mass index.
^aAll risk factors reflect measurements taken at adulthood, either at cohort baseline or at the time of the mammogram, except for early life body size, which reflects recalled values from childhood.
^bModels include adjustments for age and breast cancer case-control status.
^cModels include adjustments for age, predicted BI-RADS density, and breast cancer case-control status.
^dAnalyses of age at natural menopause and postmenopausal hormone use were limited to postmenopausal women.

Quick links

Search