Table 1 Definitions commonly used in the literature for MHO

From: Whole-genome transcriptomic insights into protective molecular mechanisms in metabolically healthy obese African Americans

Definition 1

Definition 2

Definition 3

Basic MHO definition

Modified Wildman et al. definition

Includes inflammatory status

∙ No hypertension (BP ≤ 130/85 mmHg, no BP medication)

∙ No hypertension (BP ≤ 130/85 mmHg, no BP medication)

∙ Definition 2+

∙ No diabetes (glucose ≤ 126 mg/dl)

∙ No pre-diabetes or diabetes (glucose ≤ 100 mg/dl)

∙ hsCRP ≤ 0.3 mg/dl)

∙ HDL-C ≥ 40 mg/dl for male

∙ HOMA ≤ 5.1

∙ Karelis et al. (cut off for CRP)

HDL-C ≥ 50 mg/dl for female

∙ TG/HDL ≤ 1.65 for male

∙ All conditions must be met

∙ All conditions must be met

TG/HDL ≤ 1.32 for female

 
 

∙ All conditions must be met

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