Fig. 2
From: Predictors of next-generation sequencing panel selection using a shared decision-making approach

The National Cancer Centre Singapore model of care for genetic counseling, employing a shared decision-making (SDM) approach for NGS panel selection. It involves a process of the following three phases of communication: (i) choice talk, where the patient is made aware that choice exists; (ii) option talk, where patients are informed about the NGS panel options in greater detail; and (iii) decision talk, where patient decision-making and preferences are supported by exploring ‘what matters most to them’. Patients journey from their initial preferences to informed preferences, through a process of deliberation and along the way are provided with decision support by their clinician. VUS variant of uncertain significance, NGS next-generation sequencing, CGS Cancer Genetics Service