Fig. 2
From: Both rare and common genetic variants contribute to autism in the Faroe Islands
Rare CNVs in Faroese individuals. Rare copy-number variant (CNV) analysis among gene-set lists within Faroe individuals (XHMM CNV calling from WES and CNV frequency < 0.01 in controls). The number of exonic CNV carriers altering any gene or gene-set lists (SFARI genes, pLI > 0.9 genes and Brain genes, see Materials and Methods section) were compared between individuals with autism, siblings and controls (one-sided Fisher’s exact test: nautism = 36, nsib = 28, ncontrols = 107, pCNV_loss_SFARI = 0.035, ORCNV_loss_All_SFARI = 6.56; pCNV_loss_pLI>0.9 = 0.014, ORCNV_loss_pLI>0.9 = 13.25; pCNV_gain_All_genes = 0.005, ORCNV_gain_All_genes = 3.09; pCNV_gain_SFARI = 0.035, ORCNV_gain_All_SFARI = 6.56; pCNV_gain_Brain = 0.003*, ORCNV_gain_All_Brain = 5.61; *indicates the one withstanding Bonferroni correction for 12 tests; for families with multiple siblings, only one sibling was kept (closest on age)). Error bars represent confidence interval
