Fig. 4
From: Both rare and common genetic variants contribute to autism in the Faroe Islands
Distribution of the genome-wide polygenic score for autism in Faroese individuals. a Distribution of the genome-wide polygenic score for autism (GPS-autism) of controls, autisms and siblings (one-sided Mann Whitney U-test: nautism = 36, ncontrol = 176, nsibling = 55; Ucontrol.vs.autism = 2460, pcontrol.vs.autism = 0.017; Q1autism = 0.0009, Q2autism = 0.0011; Q3autism = 0.0012, Q1control = 0.0009, Q2control = 0.0010, Q3control = 0.0011, Q1sibling = 0.0009, Q2sibling = 0.0011 and Q3sibling = 0.0012). b Distribution of the GPS-autism for the cases without intellectual disability (ID) and the cases with ID (one-sided Mann Whitney U-test: nautism-with-ID = 12, nautism-without-ID = 24; UID.vs.no-ID = 91, pID.vs.no-ID = 0.039; Q1no-ID = 0.0010, Q2no-ID = 0.0012; Q3no-ID = 0.0013, Q1ID = 0.0008, Q2ID = 0.0009, Q3ID = 0.0012). The GPS was calculated using PRSice-2 (see methods section, P-value threshold of 0.2 and R2 of 0.036). P-values were computed on data adjusted for principal component ancestry and for inbreeding
