Table 1 Familial and sporadic ALS SOD1 mutation carrier samples.

From: Identity by descent analysis identifies founder events and links SOD1 familial and sporadic ALS cases

Familial or sporadic

Family or sporadic ID

Number of samples

Number of pairsa

SOD1 mutation

Sporadic

SALS

3

–

p.I114T

Familial

3

6

15

p.E101G

Familial

12

15

105

p.I114T

Familial

18

32b

496

p.V149G

Familial

35

1

0

p.V149G

Familial

43

2

1

p.I114T

Familial

76

1

0

p.I114T

Familial

95

2

1

p.I114T

Familial

98

1

0

p.I114T

Familial

106

1

0

p.I114T

Familial

123

1

0

p.I114T

Familial

124

2

1

p.I114T

Familial

130

1

0

p.I114T

Familial

131

1

0

p.I114T

Familial

132

3

3

p.E101G

Familial

197

2

1

p.I114T

Familial

213

1

0

p.I114T

Familial

259

1

0

p.I114T

Familial

267

1

0

p.I114T

Familial

270

1

0

p.I114T

Familial

274

1

0

p.I114T

Familial

286

1

0

p.I114T

Familial

334

2

1

p.I114T

Familial

374

2

1

p.I114T

Familial

mq10

1

0

p.I114T

Familial

mq36

1

0

p.I114T

Total

–

86

625

–

  1. aThe number of pairwise comparisons between samples was calculated for familial samples only and was simply the number of unordered 2-sample combinations, i.e. n-choose-2, where n was the number of samples.
  2. bWGS data from five additional samples did not pass WGS-processing quality thresholds and were not used in subsequent analyses.
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