Fig. 1: Overview of 5hmC in cfDNA between DLBCL and FL. | npj Genomic Medicine

Fig. 1: Overview of 5hmC in cfDNA between DLBCL and FL.

From: Alterations of 5-hydroxymethylation in circulating cell-free DNA reflect molecular distinctions of subtypes of non-Hodgkin lymphoma

Fig. 1

a Normalized counts of 5hmC reads show distinct distributions in the human genome. b The 294 differentially modified genes between DLBCL and FL are shown. c The distribution of the 294 differentially modified genes between DLBCL and FL is shown across the human genome. d A small proportion of genes drive the overall differential modification between DLBCL and FL. Red indicates differentially modified genes with P-value < 1 × 10−4. 3′TR 3′ untranslated region, 5′UTR 5′ untranslated region, CGI CpG islands, DLBCL diffuse large B-cell lymphoma, FL follicular lymphoma, UD DLBCL of unknown cell-of-origin, GCB germinal center B-cell-like DLBCL, ABC activated B-cell-like DLBCL.

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