Fig. 7: KLF5 knockdown inhibits tumor growth in vivo by regulating the DANCR/miR-194/AKT2 axis. | npj Genomic Medicine

Fig. 7: KLF5 knockdown inhibits tumor growth in vivo by regulating the DANCR/miR-194/AKT2 axis.

From: KLF5 activates lncRNA DANCR and inhibits cancer cell autophagy accelerating gastric cancer progression

Fig. 7

A qRT-PCR to determine the expression of KLF5, DANCR, miR-194, and AKT2 in nude mouse tumor tissue; B western blot assay to measure the protein expression of KLF5 and AKT2 in nude mouse tumor tissue; C quantitative analysis of tumor volume growth in nude mice; D quantitative analysis of tumor weight in nude mice; *p < 0.05, **p < 0.00, ***p < 0.0001. The measurement data are summarized by mean ± standard deviation. Data in A, B, D were analyzed by unpaired t test. Statistical analysis in relation to time-based measurements in C was realized using repeated measures ANOVA, followed by a Bonferroni’s post hoc test.

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