Fig. 1: Pedigrees of thirteen families with BGN variants identified in the current study.
From: Expanding the clinical spectrum of biglycan-related Meester-Loeys syndrome
Circle = female. Square = male. Diamond = unknown sex. Filled = patients with connective tissue features. Unfilled = unaffected or asymptomatic person. Strikethrough = deceased person. + = hemi-/heterozygous BGN variant carrier. (+) = heterozygous BGN variant carrier reported by proband. – = tested negative for BGN variant. Arrow = proband.
